| dc.identifier.citation | Abdul, Gapar, Nor, Adilah, Asem, Nornaimah, Abd, Hapit, Nor, Hussaini, MAS, Mohamed, Omar, Azam, & Eshaifol. (2023). Phytochemical Profiling and Anticancer Activities of Ethanolic and Queous Propolis Extract of Trigona apicalis. Journal of Health and Translational Medicine, sp2023(1), 141– 148. https://doi.org/10.22452/jummec.sp2023no1.13 Blevins, M., Hallie, Xu, Yiming, Biby, Savannah, Zhang, & Shijun. (2022). The NLRP3 Inflammasome Pathway: A Review of Mechanisms and Inhibitors for the Treatment of Inflammatory Diseases. Frontiers in Aging Neuroscience, 14(June), 1–27. https://doi.org/10.3389/fnagi.2022.879021 Candra, Gede, Ngurah, Hadi, Wijaya, Made, I, Al, Adnyana, Et, & Partha. (2021). Molecular Docking Kaempferol sebagai Antiinflamasi pada Aterosklerosis secara In Silico. Jurnal Ilmiah Medicamento, 7(1), 13–18. https://doi.org/10.36733/medicamento.v7i1.1497 Chen, Ying, Ye, Xingyan, Escames, Germaine, Lei, Wangrui, Zhang, Xin, Li, Meng, Jing, Tong, Yao, Yu, Qiu, Zhenye, Wang, … Yang. (2023). The NLRP3 inflammasome: contributions to inflammation- related diseases. Cellular & Molecular Biology Letters, 28(1), 51. https://doi.org/10.1186/s11658- 023-00462-9 Cui, Yifeng, Dong, Qiwen, Hong, Daocheng, Wang, & Xikun. (2019). Predicting protein-ligand binding residues with deep convolutional neural networks. BMC Bioinformatics, 20(1), 1–12. https://doi.org/10.1186/s12859-019-2672-1 Dinata, I, D., Peni1, I, M., Asnawi1, Aiyi, Ligan, Identifikasi, Receptor, Angiotensin, Ii, Blocker, Pegagan, & Ekstrak, D. (2023). Identification of Angiotensin Receptor Blocker II Ligands From Gotu Kola (Centella asiatica L.) Extract: an In Silico Study. Indonesian Journal of Pharmaceutical Science and Technology Journal Homepage, 5(2), 196–206. http://jurnal.unpad.ac.id/ijpst/ Effendi, N., Saputri, N. A., Purnomo, H., & Aminah, A. (2023). In Silico ADME-T dan Molekular Docking Analog Tamoxifen Sebagai Kandidat Agen Terapi Kanker Payudara. Media Farmasi, 19(1), 9. https://doi.org/10.32382/mf.v19i1.3305 Erizon, Erizon, Karani, & Yerizal. (2020). Hdl Dan Aterosklerosis. Human Care Journal, 5(4), 1123. https://doi.org/10.32883/hcj.v5i4.851 Fadlan, Arif, Nusantoro, Yesaya, & Reformyada. (2021). The Effect of Energy Minimization on The Molecular Docking of Acetone-Based Oxindole Derivatives. JKPK (Jurnal Kimia Dan Pendidikan Kimia), 6(1), 69. https://doi.org/10.20961/jkpk.v6i1.45467 Fakih, Muhammad, T., Putri, Prastowo, N. W. R., Marillia, Viola, Ramadhan, Fitra, D. S., Darusman, & Fitrianti. (2022). Identifikasi Aktivitas Biologis, Prediksi Toksisitas, dan Molecular Docking Senyawa Jubanine dari Tanaman Bidara Arab sebagai Kandidat Antivirus SARS-CoV-2. Jurnal Riset Kimia, 13(1), 111–121. https://doi.org/10.25077/jrk.v13i1.437 Frimayanti, Neni, Nasution, Rahmah, Musyirna, Etavianti, & Elsa. (2021). Molecular docking and molecular dynamic simulation of 1,5-benzothiazepine chalcone derivative compounds as potential inhibitors for Zika virus helicase. Jurnal Riset Kimia, 12(1), 44–52. https://doi.org/10.25077/jrk.v12i1.365 Gonzale, L., Irene, Amesty, Ángel, Estévez-Braun, Ana, Heras, de las, Beatriz, Hortelano, & Sonsoles. (2022). Dehydroisohispanolone as a Promising NLRP3 Inhibitor Agent: Bioevaluation and Molecular Docking. Pharmaceuticals, 15(7). https://doi.org/10.3390/ph15070825 Hasan, R., I’anah, F. C., & Bahi, R. R. R. (2022). Docking Molekuler Senyawa Potensial Daun Kelor (Moringa oleifera) Terhadap Reseptor Folat. Journal of Innovation Research and Knowledge, 2(2), 519–526. Honda, Bandeira, Seeko, Tamisa, Ku, John, Anders, Joachim, & Hans. (2023). Cell type-speci fi c roles of NLRP3 , in fl ammasome- dependent and -independent , in host defense , sterile necroin fl ammation , tissue repair , and fi brosis. July, 1–12. https://doi.org/10.3389/fimmu.2023.1214289 Idacahyati, K., Nofianti, T., Aswa, G. A., & Nurfatwa, M. (2020). Hubungan Tingkat Kejadian Efek Samping Antiinflamasi Non Steroid dengan Usia dan Jenis Kelamin. Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia, 6(2), 56. https://doi.org/10.20473/jfiki.v6i22019.56-61 Ipav, S. S., Igoli, J. O., Tor-Anyiin, T. A., & Anyam, J. V. (2022). Isolation and Characterisation of Alpha and Beta Amyrins From Propolis Obtained From Benue State. Journal of Chemical Society of Nigeria, 47(2), 250–261. https://doi.org/10.46602/jcsn.v47i2.723 Ischak, Ino, Netty, Musa, JA, Weny, Aman, Ode, La, Alio, La, Kilo, La, Akram, Saleh, Deltalia, & Sri. (2023). Studi Molecular Docking dan Prediksi ADME Senyawa Metabolit Sekunder Tumbuhan Obat Tradisional Gorontalo terhadap Reseptor HER-2 sebagai Antikanker Payudara. Jamb.J.Chem, 5(1), 90–103. https://www.rcsb.org/. Jabin, Anika, Uddin, Fahim, Mohammad, Azad, A., Salauddin, Rahman, Ashfaque, Tabassum, Fawzia, Sarker, Pritthy, Morshed, Helal, M, A. K., Rahman, Samiur, Raisa, … Maryam. (2023). Target- specificity of different amyrin subunits in impeding HCV influx mechanism inside the human cells considering the quantum tunnel profiles and molecular strings of the CD81 receptor: a combined in silico and in vivo study. In Silico Pharmacology, 11(1). https://doi.org/10.1007/s40203-023-00144-6 Kemenkes, Republik, & Indonesia. (2018). Kementerian Kesehatan RI. Profil Laporan Nasional Riset Kesehatan Dasar (Riskesdas). Kim, & Sunghwan. (2021). Exploring Chemical Information in PubChem. Current Protocols, 1(8). https://doi.org/10.1002/cpz1.217 Kong, P., Cui, Z. Y., Huang, X. F., Zhang, D. D., Guo, R. J., & Han, M. (2022). Inflammation and atherosclerosis: signaling pathways and therapeutic intervention. In Signal Transduction and Targeted Therapy (Vol. 7, Issue 1). Springer US. https://doi.org/10.1038/s41392-022-00955-7 Krisnamurti, G. C., Bare, Y., Amin, M., & Primiani, C. N. (2021). Combination of Curcumin from Curcuma longa and Procyanidin from Tamarindus indica in Inhibiting Cyclooxygenases for Primary Dysmenorrhea Therapy : In silico study. 11(1), 7460–7467. Litha, A., Abduh, I., Ilahi, K., Amini, A. R., Jurusan, D., Elektro, T., Negeri, P., Pandang, U., Jurusan, M., Elektro, T., Negeri, P., & Pandang, U. (2021). Karakterisasi Antioksidan Pada Limbah Sarang Lebah Trigona spp. dengan Metode GCMS. filtrat 1, 150–156. Montero, Mora, M. A., Wardani, & Kusuma, A. (2024). In silico study of flavonoid compounds from dadap serep (Erythrina subumbrans) twigs and roots as antipyretics. Journal of Pharmaceutical and Sciences, 7(1), 86–93. https://journal-jps.com/new/index.php/jps/article/view/483 Moriya, J. (2019). Critical roles of inflammation in atherosclerosis. Journal of Cardiology, 73(1), 22–27. https://doi.org/10.1016/j.jjcc.2018.05.010 Pharmacia, J., Waluya, M., Pharmacia, J., Waluya, M., No, V., Lestari, N. A., Isrul, M., Syah, D., & Ramadhan, F. (2024). Skrining Virtual Berbasis Farmakofor Dari Database Bahan Alam Sebagai Inhibitor Alosterik Mutan T790M / C797 EGFR Untuk Penemuan Obat Kanker Paru Pharmacophore-Based Virtual Screening From Natural Compound Database as C790M / C797 EGFR Mutant Allosteric I. Jurnal Pharmacia Mandala Waluya, 3(3), 168–186. Phuong, Lan, D. T., Phuong, V., Nguyen, Tuan, L., Nguyen, Cong, Thanh, N., Hang, Thu, N., Thanh, Nguyen, L., Hue, Thi, V., Vuong, Quoc, N., Ha, Thu, N. T., Popova, … Vassya. (2023). Antimicrobial, Cytotoxic, and α-Glucosidase Inhibitory Activities of Ethanol Extract and Chemical Constituents Isolated from Homotrigona apicalis Propolis—In Vitro and Molecular Docking Studies. Life, 13(8), 1–14. https://doi.org/10.3390/life13081682 Prabhu, S. R. (2023). Inflammation: An Overview. In Textbook of General Pathology for Dental Students (pp. 41–47). Springer Nature Switzerland. https://doi.org/10.1007/978-3-031-31244-1_6 Sari, Mitra, Ayu, Kusuma, Wijaya, Irwawan, Yani, Sinar, Arunga, Tangke, & Enos. (2024). Aktivitas Antibakteri Dari Propolis Lebah (Homotrigona apicalis). 7. Sen, D. J., Nandi, K., & Saha, D. (2021). Rule of Five: The Five Men Army to Cross The Blood Brain Barrier for Therapeutically Potent. World Journal of Advance Healthcare Research, 5(3), 206–211. https://www.researchgate.net/publication/351945081 Siregar, Khalish, Khairy, Al, Arsy, Syaifie, Hawa, Putri, Jauhar, Miftah, Muhammad, Arda, Gaisani, Adzani, Rochman, Taufiqu, Nurul, Kustiawan, Mariana, … Etik. (2024). Revealing curcumin therapeutic targets on SRC, PPARG, MAPK8 and HSP90 as liver cirrhosis therapy based on comprehensive bioinformatic study. Journal of Biomolecular Structure and Dynamics, 0(0), 1–18. https://doi.org/10.1080/07391102.2023.2301534 Sukmawati, D. (2023). Peran Penting Inflamasom NLRP3 pada Aterosklerosis. Jurnal Penyakit Dalam Indonesia, 10(2). https://doi.org/10.7454/jpdi.v10i2.1417 Syahroni, E., Wisnuwardani, H. A., & Fakih, T. M. (2020). Studi In Silico Senyawa Turunan Phthalosianin terhadap Reseptor HasAp pada Bakteri Pseudomonas aeruginosa sebagai Kandidat Fotosensitizer. Prosiding Farmasi, 6(2), 352–361. Szarka, András, Lőrincz, Tamás, Hajdinák, & Péter. (2022). Friend or Foe: The Relativity of (Anti)oxidative Agents and Pathways. International Journal of Molecular Sciences, 23(9). https://doi.org/10.3390/ijms23095188 Winardi, D. O., Alliyah, S. A., Fadilah, S. N., Sirait, J., Putra, H. B. A., Puspitadewi, N., Neli, N., Muchtaridi, M., & Zuhrotun, A. (2023). Studi In Silico dan In Vitro Senyawa Aktif pada Rimpang Kunyit (Curcuma domestica) sebagai Antiinflamasi pada Cyclooxygenase-2 (COX-2). Indonesian Journal of Pharmaceutical Science and Technology, 1(1). https://doi.org/10.24198/ijpst.v0i0.47171 Wulandari, Prasiska, Gabriel, Rizky, Nurdin, Aulia, Kevin, F., Hanna, Halwa, Pakhrul, Diffa, Harits, Salmandhiya, Prameswari, Sabiq, Pribadi, Agustina, Natashya, … Diah. (2023). Indonesian Journal of Chemical Science In Silico Study of Secondary Metabolite Compounds in Parsley (Petroselinum crispum) as a Drug Terapy for Blood Cancer (Myeloproliferative Neoplasm (MPN)) targeting JAK- 2. Indonesian Journal of Chemical Science, 12(2), 216–228. http://journal.unnes.ac.id/sju/index.php/ijcs Xiao, Fan, Chen, Zhe, Wei, Zixiang, Tian, & Leilei. (2020). Hydrophobic Interaction: A Promising Driving Force for the Biomedical Applications of Nucleic Acids. Advanced Science, 7(16), 1–34. https://doi.org/10.1002/advs.202001048 Xie, Haibo, Peng, Jiale, Zhang, Xuesong, Deng, Lihua, Ding, Yani, Zuo, Xulei, Wang, Feng, Wu, Yonggui, Zhang, Jiaxiang, Zhu, & Qixing. (2022). Effects of mitochondrial reactive oxygen species- induced NLRP3 inflammasome activation on trichloroethylene-mediated kidney immune injury. Ecotoxicology and Environmental Safety, 244(March), 114067. https://doi.org/10.1016/j.ecoenv.2022.114067 Xu, Xiaolin, Wu, Xianli, Yue, Gengyu, An, Qimin, Lou, Jun, Yang, Xiaoxu, Jin, Zhe, Ding, Jianhong, Hu, Yanxia, Du, … Rui. (2023). The role of Nod-like receptor protein 3 inflammasome activated by ion channels in multiple diseases. Molecular and Cellular Biochemistry, 478(6), 1397–1410. https://doi.org/10.1007/s11010-022-04602-1 Yarlina, V. P. (2020). Kajian Konsentrasi Etanol dan Metode Ekstraksi Propolis dari Lebah Jenis Trigona sp. Terhadap Aktivitas Antimikroba Bakteri Escherichia coli dan Beberapa Karakteristik Ekstrak Propolis [Study of Ethanol Concentration, Propolis Extraction Method and Charac. Jurnal Teknologi & Industri Hasil Pertanian, 25(1), 27. https://doi.org/10.23960/jtihp.v25i1.27-34 Yi, Xu, Yanling, Yang, Xi, Chen, Danling, Jiang, Fei, Zhang, Yao, Guo, Bin, Hu, Guohai, Xu, Shengliang, Peng, Lidong, … Hu. (2023). NLRP3 inflammasome in cognitive impairment and pharmacological properties of its inhibitors. Translational Neurodegeneration, 12(1), 1–16. https://doi.org/10.1186/s40035-023-00381-x Zainal, W. N. H. W., Azian, N. A. A. M., Albar, S. S., & Rusli, A. S. (2022). Effects of extraction method, solvent and time on the bioactive compounds and antioxidant activity of Tetrigona apicalis Malaysian propolis. Journal of Apicultural Research, 61(2), 264–270. https://doi.org/10.1080/00218839.2021.1930958 | id_ID |